Prevalence of HTLV-I and HTLV-II infections among HIV-1-infected asymptomatic individuals in São Paulo, Brazil

Author:

CASSEB Jorge1,ARAUJO Adele CATERINO-DE2,HONG Marisa A.3,SALOMÃO Simone3,GALLO Dana4,HENDRY R. Michael4,DUARTE Alberto J.S.3

Affiliation:

1. Instituto de Infectologia Emílio Ribas; Universidade de São Paulo

2. Instituto Adolfo Lutz

3. Universidade de São Paulo

4. California Department of Health Services

Abstract

Human immunodeficiency virus (HIV-1)-infected subjects with acquired immunodeficiency syndrome (AIDS) are often infected with multiple pathogens. In particular, HTLV-I and HTLV-II infections have been found more frequently in AIDS patients than in asymptomatic individuals in Europe and Japan. We carried out a serosurvey among asymptomatic HIV-1-infected subjects in São Paulo, Brazil and compared our results with those of other investigators. In this study, we found HTLV infection in 1.5% of 266 asymptomatic and 14% of 28 AIDS patients. Epidemiological data obtained from patients pointed out the use of intravenous drugs as the principal risk factor for acquiring retroviruses. In conclusion, our results are in accordance with other studies done in Brazil and elsewhere where the principal risk group for HIV/HTLV-I/II coinfection was IDU

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

Reference13 articles.

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2. Prevalence and risk factors of HTLV-I and HTLV-II among HIV-1 infected patients in São Paulo, SP, Brazil;CATERINO-DE-ARAUJO A.;Europ. J. Epidem.,1994

3. Classification system for human lymphotropic virus type III/lymphadenopathy-associated virus infections;MMWR,1986

4. HIV-1, HIV-2, and HTLV-1 infection in high-risk groups in Brazil;CORTES E.;New Engl. J. Med.,1989

5. Reciprocal activation of human T-lymphotropic viruses in HTLV-I transformed cells superinfected with HIV-1;DE ROSSI A.;J. Acquir. Immune Defic. Syndr,1991

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