Three year seroepidemiological study of varicella-zoster virus in São Paulo, Brazil

Author:

YU Ana Lúcia Frugis1,COSTA Jane Margarete1,AMAKU Marcos1,PANNUTI Cláudio Sérgio1,SOUZA Vanda Akico Ueda Fick de1,ZANETTA Dirce Maria Trevisan1,BURATTINI Marcelo Nascimento1,MASSAD Eduardo1,AZEVEDO Raymundo Soares1

Affiliation:

1. Universidade de São Paulo, Brazil

Abstract

A serosurvey of varicella has been carried out in children attending the public school network of São Paulo city, Brazil, from 1992 to 1994. This study was performed in order to establish the age related prevalence of antibodies against varicella-zoster virus (VZV) and its age specific transmission dynamics pattern in these children. Among 2500 schools in the city of São Paulo public network, 304 were randomly selected; 7 children of a given age (ranging from 1 to 15 years) were randomly selected in each school, and blood samples were obtained by fingerprick into filter paper. Blood eluates were analyzed for the presence of antibodies to VZV by ELISA. Proportion of seropositivity were calculated for each age group. Samples consisted of 1768 individuals in 1992, 1758 in 1993, and 1817 in 1994, resulting in 5343 eluates. A high proportion of seropositive children from 1 to 3 years of age was observed, ascending until 10 years of age and reaching a plateau around 90% afterwards. VZV transmission in this community was similar along the three years of the study. In children attending public schools in the city of São Paulo, contact with VZV occurs in early childhood. If immunization against VZV is considered it should be introduced as soon as possible.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

Reference15 articles.

1. Varicella vaccine trials in healthy children;ARBETER A.M.;Amer. J. Dis. Child.,1984

2. Clinical trials of varicella vaccine in healthy adolescents and adults;ARBETER A.M.;Infect. Dis. Clin. N. Amer.,1996

3. Administration of live attenuated varicella vaccine to children with cancer before starting chemotherapy;CRISTÓFANI L.M.;Vaccine,1991

4. Varicella-zoster virus epidemiology: A changing scene?;FAIRLEY C. K.;J. infect. Dis.,1996

5. Age-specific incidence of chickenpox;FINGER R.;Publ. Hlth. Rep.,1994

Cited by 15 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3