Fatty acid and phospholipase A2 plasma levels in children with autism-Reference-Cited by-同舟云学术

Fatty acid and phospholipase A2 plasma levels in children with autism

Published:2013 Issue:1 Volume:35 Page:76-80
ISSN:2237-6089
Container-title:Trends in Psychiatry and Psychotherapy
language:
Short-container-title:Trends Psychiatry Psychother.

Author:

Tostes Márcia Helena Fávero de Souza¹,Polonini Hudson Caetano¹,Mendes Rosemeri¹,Brandão Marcos Antônio Fernandes¹,Gattaz Wagner Farid²,Raposo Nádia Rezende Barbosa¹

Affiliation:

1. Universidade Federal de Juiz de Fora, Brazil

2. Universidade de São Paulo, Brazil

Abstract

OBJECTIVE: To evaluate fatty acid plasma levels, phospholipase A2 activity, and the developmental profiles of children with autism vs. control subjects. METHODS: Twenty four children with autism underwent laboratory analysis for fatty acid quantification using gas chromatography and PLA2 activity determination by fluorometric assay. RESULTS: No correlation was observed between the developmental quotient and fatty acid plasma levels. Phospholipase A2 activity was significantly higher among autistic children compared with controls. CONCLUSION: The study did not show a correlation between fatty acid and phospholipase A2 plasma levels and the developmental profile of children with autism.

Publisher

FapUNIFESP (SciELO)

Subject

Psychiatry and Mental health,General Medicine

Link

http://www.scielo.br/pdf/trends/v35n1/a09v35n1.pdf

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