Advances in bacterial specific imaging

Author:

Wareham David1,Michael J.2,Das Satya1

Affiliation:

1. St Bartholomew's Hospital, UK; Institute of Cell and Molecular Science; University of London, UK

2. St Bartholomew's Hospital, UK

Abstract

Nuclear medicine is a powerful diagnostic technique able to detect inflammatory foci in human disease. A wide range of agents have been evaluated for their ability to distinguish lesions due to microbial infection from those due to sterile inflammation. Advances continue to be made on the use of radiolabelled antibiotics which as well as being highly specific in the diagnosis of infection may be useful in monitoring the treatment and course of disease. Here we provide an update on in-vitro and clinical studies with a number of established and novel radiopharmaceuticals

Publisher

FapUNIFESP (SciELO)

Subject

Multidisciplinary

Reference32 articles.

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4. Comparison of Tc-99m Ciprofloxacin (Infecton) and Tc- 99m Methylene diphosphonate (MDP) Three-phase Bone Scintigraphy in the Diagnosis of Osteomyelitis in Patients with Sickle Cell Disease;Bererhi H;World J Nucl Med,2003

5. Imaging bacterial infections with radiolabeled 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-iodouracil;Bettegowda C;Proc Natl Acad Sci U S A,2005

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