Affiliation:
1. Universidade Federal do Pará, Brasil
2. Universidade do Estado do Pará, Brasil
3. Hospital Universitário João de Barros Barreto, Brasil
Abstract
ABSTRACT Objective: To characterize the sociodemographic, clinical and survival profile of adult metastatic patients. Method: Retrospective cross-sectional study, with secondary data from an oncology care unit, analyzed using logistic regression, Chi-Square test and Fisher’s exact test, Kaplan-Meier and Log-Rank tests. Results: From the 678 patients, male gender, mean age 59.54 years old and low education level prevailed. The mean time between diagnosis and initiation of treatment was 89.50 days (± 58.87). Increased risk of primary cancer in the digestive tract (OR 1.42). Prevalence of adenocarcinoma (OR 1.53) and metastasis to bone (OR 2.59), lymph nodes (OR 1.75), liver and peritoneum (OR 1.42). The mean overall survival was 4.16 months and a median of 3.0 months. Conclusion: The main primary site was the digestive system, and the identification of metastases was predominantly unifocal liver in both genders. Overall patient survival was reduced by cancer progression.
Reference28 articles.
1. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Sung H;CA Cancer J Clin,2021
2. Interactions in the (pre)metastatic niche support metastasis formation;Doglioni G;Front Oncol,2019
3. Molecular principles of metastasis: a hallmark of cancer revisited;Fares J;Signal Transduct Target Ther,2020
4. Estimativas 2023: Incidência de Câncer no Brasil,2022
5. Clinical landscape of cancer metastases;Riihimäki M;Cancer Med,2018