Lung cancer and occupational exposure: hospital-based case-control study

Author:

Brey Christiane1ORCID,Consonni Dario2ORCID,Sarquis Leila Maria Mansano3ORCID,Miranda Fernanda Moura D’Almeida3ORCID

Affiliation:

1. Instituto Federal do Paraná, Brasil

2. Università degli Studi di Milano, Italia

3. Universidade Federal do Paraná, Brasil

Abstract

ABSTRACT Objective To analyze the relationship between occupation and lung cancer in patients at a national referral hospital for cancer care in southern Brazil. Method Hospital-based case-control study conducted between February and October 2019. Occupational histories were coded according to international classifications and translated into occupations associated with lung cancer (List A and B). The odds ratios were adjusted for smoking, with a 95% confidence interval, calculated by conditional logistic regression. Results 99 cases and 227 controls were included. Among men, the occupation of painters (list A) was associated with lung cancer (OR = 14.3; 95% CI: 1.8-116.5), there were no occupations in list B associated with lung cancer. In women, no increased risks were found. Conclusions It has been shown that exposure to occupational carcinogens among repair and construction painters increases the risk of lung cancer.

Publisher

FapUNIFESP (SciELO)

Subject

General Medicine

Reference20 articles.

1. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Bray F;CA Cancer J Clin,2018

2. Instituto Nacional de Câncer José Alencar Gomes da Silva. Estimativa 2020: incidência de câncer no Brasil,2019

3. Risk factors for lung cancer worldwide;Malhotra J;Eur Respir J,2016

4. International Agency for Research on Cancer. IARC Monographs on the evaluation of carcinogenic risks to humans,2014

5. Screening for occupational lung cancer: an unprecedented opportunity;Markowitz SB;Clin Chest Med,2020

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