Bone formation in sinus augmentation with different xenograft particle sizes: systematic review and meta-analysis

Author:

GENARI Bruna1ORCID,CANTARELLI Romulo2ORCID,RAMOS NETO Antonio da Silva1ORCID,SILVA Emílio Barbosa e1ORCID,DEGRAZIA Felipe Weidenbach1ORCID

Affiliation:

1. Centro Universitário do Distrito Federal, Brasil

2. Pontifícia Universidade Católica do Rio Grande do Sul, Brasil

Abstract

ABSTRACT The commercial bovine bone mineral most commonly used is available in two particle sizes and studies have demonstrated contradictory results regarding bone formation volume using small or large particles. The aim of this systematic review and meta-analysis was to compare the bone formation volume and residual bovine bone volume in sinus floor augmentation using small and large particles. The following outcome measures were assessed: bone formation volume (%) and residual bovine bone particles volume (%) assessed by histomorphometric analysis. The initial screening resulted in 236 records. After removal of duplicated articles and analysis of titles, abstracts and full texts, three articles were included in the meta-analysis. The bone formation volume and residual bovine bone volume did not differ between small and large particles, with low heterogeneity of studies. The particle size of bovine bone mineral did not influence bone formation percentage; small and large particles of bovine bone graft presented similar residual bone mineral; more randomized clinical trials should be performed to completely confirm that bovine bone mineral particle size does not affect the result of sinus floor augmentation.

Publisher

FapUNIFESP (SciELO)

Subject

General Dentistry

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