Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients

Author:

Teixeira Raquel Lima de Figueiredo1,Morato Renata Gomes1,Cabello Pedro Hernan1,Muniz Ligia Mayumi Kitada1,Moreira Adriana da Silva Rezende1,Kritski Afrânio Lineu1,Mello Fernanda Carvalho Queiroz1,Suffys Philip Noel2,Miranda Antonio Basilio de2,Santos Adalberto Rezende2

Affiliation:

1. Universidade Federal do Rio de Janeiro, Brasil

2. Fiocruz, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

Microbiology (medical)

Reference54 articles.

1. Breast cancer and CYP1A1, GSTM1 and GSTT1 polymorphisms: evidence of a lack of association in Caucasians and African Americans;Bailey LR;Cancer Res,1998

2. The influence of various genotypes on the metabolic activity of NAT2 in Chinese population;Chen B;Eur J Clin Pharmacol,2006

3. Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis;Cho HJ;Tuberculosis,2007

4. Pharmacokinetics of isoniazid metabolism in man;Ellard GA;J Pharmacokinet Biopharm,1976

5. Isoniazid hepatotoxicity associated with treatment of latent tuberculosis infection: a 7-year evaluation from a public health tuberculosis clinic;Fountain FF;Chest,2005

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