A randomized, double-blind, and placebo-controlled study with tranexamic acid of bleeding and fibrinolytic activity after primary coronary artery bypass grafting

Author:

Santos A.T.L.1,Kalil R.A.K.1,Bauemann C.1,Pereira J.B.1,Nesralla I.A.1

Affiliation:

1. Fundação Universitária de Cardiologia, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

Cell Biology,General Pharmacology, Toxicology and Pharmaceutics,General Medicine,Immunology,Physiology,Biochemistry,General Neuroscience,Biophysics

Reference25 articles.

1. Bleeding hearts;Estafanous FG;Journal of Cardiothoracic and Vascular Anesthesia,1991

2. Reexploration for bleeding is a risk factor for adverse outcomes after cardiac operation;Moulton MJ;Journal of Thoracic and Cardiovascular Surgery,1996

3. Another point of view on the mechanism of thrombin generation during cardiopulmonary bypass: role of tissue factor pathway inhibitor;Kojima T;Journal of Cardiothoracic and Vascular Anesthesia,2001

4. Plasminogen interactions with platelets in plasma;Adelman B;Blood,1988

5. The contribution of fibrinolysis to bypass bleeding;Spiess BD;Journal of Cardiothoracic and Vascular Anesthesia,1991

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