Antibiotic cement-coated plate is a viable and efficient technique for the definitive management of metaphyseal septic nonunions of the femur and tibia

Author:

BIDOLEGUI FERNANDO1ORCID,CODESIDO MARIANO2ORCID,PEREIRA SEBASTIÁN1ORCID,ABRAHAM AGUSTÍN2ORCID,PIRES ROBINSON ESTEVES3ORCID,GIORDANO VINCENZO4ORCID

Affiliation:

1. Hospital Sirio Libanés, Brazil

2. Hospital Universitario Austral, Servicio de Ortopedia y Traumatología, Argentina

3. Universidade Federal de Minas Gerais, Brazil

4. Hospital Municipal Miguel Couto, Brasil; Clínica São Vicente, Brazil

Abstract

ABSTRACT Objective: the management of septic metaphyseal nonunions is challenging, with inconsistent outcomes. Antibiotic cement-coated implants have been demonstrated good outcome for diaphyseal infected nonunions, however there is no data in metaphyseal infected nonunions. Methods: fifteen adult patients with septic metaphyseal nonunions of the femur or tibia were treated with antibiotic cement-coated plates. The antibiotic cement-coated plate was prepared with either gentamicin or vancomycin. Outcome measures were infection control, bone healing, return to pre-injury level on daily activities, and quality of life at the last follow-up visit. A p value of <5% was considered significant. Results: Methicillin-susceptible S. aureus was isolated in 53.3% cases. Average postoperative follow-up time was 18 months. Local infection control and radiographic bone healing were adequately achieved in 93.3% patients. No patient presented recurrent symptoms of surgical site infection. Fourteen patients reported to be either able, or on the same level as before injury, with 73.3% reporting no problems in all five dimensions of the EQ-5D-3L. Persistent infection was the only variable associated with a reduced long-term quality of life. Conclusion: antibiotic cement-coated plate is a viable and efficient surgical technique for the definitive management of juxta-articular metaphyseal septic nonunions of the femur and tibia.

Publisher

FapUNIFESP (SciELO)

Subject

Surgery

Reference34 articles.

1. Long bone non-unions treated with the diamond concept: a case series of 64 patients;Giannoudis PV;Injury,2015

2. Principles of nonunion management state of the art;Nauth A;J Orthop Trauma,2018

3. The multifactorial aetiology of fracture nonunion and the importance of searching for latent infection;Mills L;Bone Joint Res,2016

4. Forearm nonunion characterization and management;Srinivasan RC;J Hand Surg Am,2020

5. Infection after fracture fixation current surgical and microbiological concepts;Metsemakers WJ;Injury,2018

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3