Affiliation:
1. University of São Paulo, Brazil
Abstract
Primary biliary cirrhosis (PBC) is a cholestatic liver disease, which is characterized by a chronic inflammatory destruction of intrahepatic bile ducts. It is a rare disorder whose precise etiology is still to be elucidated. Even though the liver is the principal target of PBC, other organ systems also might be affected. Muscular involvement has rarely been described in this disease, and in the majority of cases, muscular weakness has been interpreted as polymyositis. We report the case of a 48-year-old woman suffering from classic PBC, in association with a myopathy whose histological features are distinct from the cases reported before. We also performed a MEDLINE research for PBC and concomitant muscular diseases.
Reference5 articles.
1. Autoimmune associations in primary biliary cirrhosis;CULP KS;Mayo Clin Proc,1982
2. Myopathy with mitochondrial alterations in patients with primary biliary cirrhosis and antimitochondrial antibodies;VARGA J;Arthr Rheum,1993
3. Polymyositis associated with primary biliary cirrhosis;SIMPSON WG;J Ky Med Assoc,1995
4. Hepatic osteodystrophy in primary biliary cirrhosis: effects of medical treatment;CRIPPIN JS;Am J Gastr,1994
5. Estrogen-progestogen therapy for low bone density in primary biliary cirrhosis;OLSSON R;Liver,1999
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献