FIRST REPORT OF METALLO-β-LACTAMASES PRODUCING Enterobacter spp. STRAINS FROM VENEZUELA

Author:

Martinez Dianny1,Rodulfo Hectorina E.2,Rodriguez Lucy3,Cana Luisa E.3,Medina Belkis3,Guzman Militza4,Carreno Numirin2,Marcano Daniel5,Donato Marcos De2

Affiliation:

1. IIBCAUDO, Universidad de Oriente, Venezuela; Hospital Universitario Antonio Patricio de Alcala, Venezuela

2. IIBCAUDO, Universidad de Oriente, Venezuela

3. Hospital Universitario Antonio Patricio de Alcala, Venezuela

4. Universidad de Oriente, Venezuela

5. Instituto Nacional de Higiene Dr Rafael Rangel, Venezuela

Abstract

Clinical strains of Enterobacter were isolated from Cumana's Central Hospital in Venezuela, and classified as E. cloacae (21), E. aerogenes (7), E. intermedium (1), E. sakazakii (1) and three unclassified. The strains showed high levels of resistance, especially to SXT (58.1%), CRO (48.8%), CAZ (46.6%), PIP (46.4%), CIP (45.2%) and ATM (43.3%). This is the first report for South America of blaVIM-2 in two E. cloacae and one Enterobacter sp., which also showed multiple mechanisms of resistance. Both E. cloacae showed blaTEM-1, but only one showed blaCTX-M-15 gene, while no blaSHV was detected.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

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