Analysis of the specificity of human antibodies to antigens of Leishmania braziliensis braziliensis-Reference-Cited by-同舟云学术

Analysis of the specificity of human antibodies to antigens of Leishmania braziliensis braziliensis

Published:1989-08 Issue:4 Volume:31 Page:228-234
ISSN:0036-4665
Container-title:Revista do Instituto de Medicina Tropical de São Paulo
language:
Short-container-title:Rev. Inst. Med. trop. S. Paulo

Author:

Masuda Aoi¹,Nascimento Sueli Fátima do¹,Guerra Carmem Silvia¹,Paranhos Gláucia da Silva¹,Ferreira Antonio Walter¹

Affiliation:

1. Instituto de Medicina Tropical de São Paulo

Abstract

The antigenicity of promastigotes of Leishmania braziliensis braziliensis (L. b.braziliensis) treated with 1% sodium desoxycholate in 10 mM Tris-Hcl pH 8.2 was analysed by immunoblot using as probes sera from American cutaneous leishmaniasis (ACL), American visceral leishmaniasis (AVL), schistosomiasis, malaria and Chagas' disease. The ACL sera reacted constantly with a 60 kD band. No reactivity to this protein was observed with sera from the other diseases above mentioned indicating that the 60 kD protein may be used in serodiagnosis for ACL.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,General Medicine

Link

http://www.scielo.br/pdf/rimtsp/v31n4/04.pdf

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