Affiliation:
1. Universidade de Pernambuco, Brasil; Universidade Federal de Pernambuco, Brasil
2. Universidade de Pernambuco, Brasil
Abstract
A case-control study was conducted to identify risk factors for death from tetanus in the State of Pernambuco, Brazil. Information was obtained from medical records of 152 cases and 152 controls, admitted to the tetanus unit in the State University Hospital, in Recife, from 1990 to 1995. Variables were grouped in three different sets. Crude and adjusted odds ratios, p-values and 95% confidence intervals were estimated. Variables selected in the multivariate analysis in each set were controlled for the effect of those selected in the others. All factors related to the disease progression - incubation period, time elapsed between the occurrence of the first tetanus symptom and admission, and period of onset - showed a statistically significant association with death from tetanus. Similarly, signs and/or symptoms occurring on admission or in the following 24 hours (second set): reflex spasms, neck stiffness, respiratory signs/symptoms and respiratory failure requiring artificial ventilation (third set) were associated with death from tetanus even when adjusted for the effect of the others.
Subject
Infectious Diseases,General Medicine
Reference17 articles.
1. Prognosis in Tetanus: Use of data from therapeutic trials;ARMITAGE P.;J. infect. Dis.,1978
2. Tetanos;BETANCUR J.;Acta méd. colomb.,1987
3. Mandell, Douglas and Bennett's principles and practice of Infectious Diseases;BLECK T.P.,1995
4. Tetanus: pathophysiology, management, and prophylaxis;BLECK T.P.;Dis. Month,1991
5. Treatment of tetanus;COLE L.;Lancet,1969
Cited by
11 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献