CD14 genotype and functional dichotomy of CD14+ and CD14- cells are associated with activated immune response and development of Chagas dilated cardiomyopathy

Author:

Costa Germano Carneiro1ORCID,Rocha Manoel Otávio da Costa2,Souza Paulo Eduardo Alencar de3,Melo Diego Felipe SA2,Moreira Paula Rocha2,Gollob Kenneth John4,Nunes Maria do Carmo Pereira2,Dutra Walderez Ornelas5

Affiliation:

1. Universidade Federal de Viçosa, Brazil

2. Universidade Federal de Minas Gerais, Brazil

3. Pontifícia Universidade Católica de Minas Gerais, Brazil

4. AC Camargo Cancer Center, Brazil; Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais, Brasil

5. Universidade Federal de Minas Gerais, Brazil; Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais, Brasil

Publisher

FapUNIFESP (SciELO)

Subject

Microbiology (medical)

Reference15 articles.

1. Monocytes from patients with indeterminate and cardiac forms of Chagas' disease display distinct phenotypic and functional characteristics associated with morbidity;Souza PE;Infect Immun,2004

2. Trypanosoma cruzi infection induces differential modulation of costimulatory molecules and cytokines by monocytes and T cells from patients with indeterminate and cardiac Chagas' disease;Souza PE;Infect Immun,2007

3. Co-infection with distinct Trypanosoma cruzi strains induces an activated immune response in human monocytes;Magalhães LMD;Parasite Immunol,2019

4. The genetics of CD14 in allergic disease;Koppelman GH;Curr Opin Allerg Clin Immun,2003

5. Post-hoc analysis on the CD14 C (-260) T promoter polymorphism and coronary heart disease;Porsch-Özcürümez M;Physiol Res,2007

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