Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature-Reference-Cited by-同舟云学术

Human herpesvirus 6: report of emerging pathogen in five patients with HIV/AIDS and review of the literature

Published:2011-08 Issue:4 Volume:44 Page:522-525
ISSN:0037-8682
Container-title:Revista da Sociedade Brasileira de Medicina Tropical
language:
Short-container-title:Rev. Soc. Bras. Med. Trop.

Author:

Corti Marcelo¹,Villafañe Maria Florencia¹,Trione Norberto¹,Mamanna Lilia²,Bouzas Belén²

Affiliation:

1. Hospital de Enfermidades Infecciosas Francisco Javier Muñiz, Argentina

2. Hospital de Doenças Infecciosas Francisco Javier Muñiz, Argentina

Abstract

The reactivation of human herpesvirus 6 (HHV-6) in patients with AIDS can result in an acute and severe diffuse meningoencephalitis. We describe the epidemiological, clinical and outcome findings of five patients with diagnosis of HIV/AIDS and central nervous system involvement (CNS) due to HHV-6. Fever was present in all the patients. Meningeal compromise, seizures and encephalitis were present in some of the patients. Polymerase chain reaction (PCR) of cerebrospinal fluid (CSF) specimens was positive for HHV-6 in all the patients. HHV-6 should be included among opportunistic and emerging pathogens that involve the CNS in patients with AIDS.

Publisher

FapUNIFESP (SciELO)

Subject

Infectious Diseases,Microbiology (medical),Parasitology

Link

http://www.scielo.br/pdf/rsbmt/v44n4/26.pdf

Reference10 articles.

1. Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders;Salahuddin SZ;Science,1986

2. Seroepidemiology of human herpesvirus 6 infection in normal children and adults;Okuno T;J Clin Microbiol,1989

3. Human Herpesvirus-6 asociated retrobulbar optic neuritis in an HV-infected patient: response to antiherpes therapy and long term outcome;MéchaÏ F;J Med Virol,2007

4. Polymerase chain reaction on cerebrospinal fluid for diagnosis of virus associated opportunistic diseases of the central nervous system in HIV-infected patients;Cinque P;AIDS,1996

5. Human herpesvirus 6 in cerebrospinal fluid of patients infected with HIV: frequency and clinical significance;Bossolasco S;J Neurol Neurosurg Psyquiatry,1999

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