PERCUTANEOUS TREATMENT OF ANEURYSMAL BONE CYST WITH CALCITONIN AND METHYLPREDNISOLONE

Author:

Oliveira Marcelo Bragança dos Reis1ORCID,Meohas Walter2ORCID,Silva Ronan Ribeiro3ORCID,Carvalho Gustavo Sobral de4ORCID,Mello Fernanda Carvalho de Queiroz5ORCID,Paschoal Marcos Eduardo Machado5ORCID

Affiliation:

1. Instituto Nacional de Traumatología e Ortopedia, Brazil; Universidade Federal do Rio de Janeiro, Brazil; Escola de Saúde do Exército, Brazil

2. Instituto Nacional de Traumatología e Ortopedia, Brazil

3. Escola de Saúde do Exército, Brazil

4. Universidade Federal do Rio de Janeiro, Brazil; Escola de Saúde do Exército, Brazil

5. Universidade Federal do Rio de Janeiro, Brazil

Abstract

ABSTRACT Objective: To introduce the intralesional calcitonin and methylprednisolone percutaneous injection method, which results in the promotion of primary aneurysmal bone cyst (ABC) healing. Methods: A retrospective cohort study involving 76 patients diagnosed with ABC was performed between 2005 and 2014. Patients treated with calcitonin and methylprednisolone injection and who underwent more than 2 years of follow-up were considered eligible for the study (n=47). The Enneking staging and Capanna classification systems were used during the initial evaluation. Treatment response was assessed by Rastogi radiographic grading based on the degree of healing. X2 and Wilcoxon signed-rank tests and odds ratio calculations were used in the statistical analysis with a 5% significance level. Results: The proximal tibia extremity was the most commonly affected site (17.0%). Thirty-three (70.3%) ABC cases were staged as B3 and 28 (59.7%) were classified as type II. The average number of injections performed was 2.8 per patient, with an average reduction of the initial lytic area of 83.7% (p-value=0.00001). Satisfactory results for 91.4% (n=43; p-value=0.00001) were obtained and 5 recurrences occurred. No side effects were observed. Conclusion: Intralesional calcitonin and methylprednisolone percutaneous injection is a minimally invasive, effective, and safe method for promoting primary ABC healing. Level of evidence IV, Type of study: case series.

Publisher

FapUNIFESP (SciELO)

Subject

Rehabilitation,Physical Therapy, Sports Therapy and Rehabilitation,Orthopedics and Sports Medicine

Reference20 articles.

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3. Aneurysmal bone cyst: a 19-case series managed by percutaneous sclerotherapy;Batisse F;Orthop Traumatol Surg Res,2016

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3. Minimally invasive treatment of aneurysmal bone cysts: Systematic literature review;Orthopaedics & Traumatology: Surgery & Research;2022-06

4. Traitement non invasif du kyste osseux anévrismal : revue systématique;Revue de Chirurgie Orthopédique et Traumatologique;2022-06

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