Affiliation:
1. University Federal of Goiás; Biological Institute of São Paulo
2. Biological Institute of São Paulo
3. University Federal of Goiás
Abstract
The plant of the genus Pterodon (Fabaceae, Leguminosae), commonly known as 'sucupira' or 'faveira', are disseminated throughout the central region of Brazil and has frequently been used in popular medicine for its anti-rheumatic, analgesic, and anti-inflammatory properties. In recent years, interest in these plants has increased considerably. The biological effects of different phytoextracts and pure metabolites have been investigated in several experimental models in vivo and in vitro. The literature describes flavonoids, triterpene and steroids, while one paper presented studies with proteins isolated from the genus. This review provides an overview of phytochemical and pharmacological research in Pterodon, showing the main chemical compounds studied to date, and focusing on the relationship between these molecules and their biological activity. Furthermore, this study paves the way for more in-depth investigation, isolation and characterization of the molecules of this plant genus.
Subject
General Pharmacology, Toxicology and Pharmaceutics
Reference55 articles.
1. Further isoflavones;ALMEIDA M.E.L;Pterodon apparicioi. Phytochemistry,1975
2. Kunitz type Bauhinia bauhinioides inhibitors devoid of disulfide bridges: isolation of the cDNAs, heterologous expression and structural studies;ARAÚJO A.P.U;Biol. Chem,2005
3. Further diterpenoids isolated from Pterodon polygalaeflorus;ARRIAGA A.M.C;J. Braz. Chem. Soc.,,2000
4. The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases- a review;BASSO L.A;Mem. Inst. Oswaldo Cruz,2005
5. Chemistry of Brazilian Leguminosae;BRAZ FILHO R;XXXIV Isoflavones of Pterodon pubescens. Phytochemistry
Cited by
29 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献