Abstract
Introduction: Cancer is an important outcome after kidney transplantation because of immunosuppression and it is the second leading cause of death. The excess risk of cancer after transplantation is approximately two to three times higher than the age- and sex-matched general population, driven largely by viral- and immune-related cancers. Case presentation: 68 yr old male with single transplanted kidney and no tobacco habit presented with multiple primary malignancy over 8 yr period from carcinoma soft palate, carcinoma rectum and Hepatocellular carcinoma. Diagnosis: Patient underwent Radiation alone for softplate carcinoma, Surgery followed by chemo radiation for carcinoma rectum and Hepatocellular carcinoma. Patient on follow up PET CT and MRI have no active disease Conclusion: Carcinoma incidence is inevitable for renal transplant patient. With multimodality approach of surgery, Radiation and chemotherapy patient having a better quality of life