Production of therapeutic oral vaccines from transgenic plants –a promising way in treatment of diseases

Abstract

Discovery of vaccines is the most remarkable invention made in the field of science. These have shown to be successful when produced in animals but come with a lot of limitations. A striking invention was seen when the same vaccines could be produced in plants overcoming the disadvantages of animal vaccines. In this review, there is a detailed description underlying the need of producing vaccines in plants, why use plants as a host to produce vaccines, advantages of producing plant vaccines, existing technologies used in the production of plant vaccines and the strategies that can be employed in increasing its production. The review also focuses on how the small size of the plant genome can be utilized in order to bring about several genetic modifications making them resistant to different platforms in order to integrate the gene of interest. The review also shows lists of recombinant, oral vaccines produced through different technologies produced in plants.