Comparison of prolactin, follicle-stimulating hormone, luteinizing hormone, estradiol, thyroid-stimulating hormone, free thyroxine and body mass index between infertile and fertile Saudi women

Abstract

The objective of this study was to compare the levels of prolactin, FSH, LH, E2, TSH, FT4 and BMI between infertile Saudi women with high prolactin and fertile Saudi women with normal prolactin. The study individuals were divided into two groups; infertile Saudi women with high prolactin (Group 1) and fertile Saudi women with normal prolactin (Group 2). This study used the ARCHITECT i1000SR immunoassay analyzer for the assessment of all serum hormones. The prolactin in Group 1 was higher than in the Group 2. The FSH and LH values were similar in both groups. The TSH in Group 1 was higher than in the Group 2. The FT4 values were similar in both groups. The BMI in both groups was greater than 25 (all patients were in over weight category). In Group 1, 40% women were over weight and in Group 2, 39 % women were over weight. The rate of failed cycles in group 1 was higher than in Group 2, also cases of PCOS in Group 1 were more than in the Group 2. The rate of positive pregnancy in Group 1 is lower than in the Group 2. The results of this study demonstrated that increased levels of prolactin and TSH are among the causes of infertility in Saudi women.