Abstract
Syphilitic infection in newborn could be a devastating disease with upward trend in incidence. The prevalence rate of this disease is around 5 to 100,000 neonates and 60% of them are asymptomatic. There is two clinical forms: early and late. Infected infants may suffer severe sequelae, including cerebral palsy, hydrocephalus, sensorineural hearing loss and musculoskeletal deformity, all of which may be prevented with timely treatment during pregnancy. Questions about the prevention and management of congenital syphilis persist because the diagnosis of suspected cases and management may be confusing, and the potential for severe disability is high when cases are missed. The case here presented is an early case with any lesions in the newborn. The treatment was a successful and after there was not any complications.