Antibiotics resistance pattern of Pseudomonas aeruginosa isolated from different hospitals in Nowshera KPK Pakistan

Author:

Iqbal AsifORCID,Ahmad Iftikhar,Ali Sohail,Khattak Rabia

Abstract

Pseudomonas aeruginosa is an invasive nosocomial pathogen of immunocompromised individuals that mainly affects the respiratory system, urinary tract, burns, and wounds, as well as blood diseases. In this investigation, samples from pus, wound swabs, sputum, blood, and urine were collected to examine the isolation, biochemical identification, and antibiotic resistance pattern against antibiotics of Pseudomonas aeruginosa in Qazi Medical Complex (QMC) and District Headquarter Hospital (DHQ) Nowshera, KPK Pakistan. For biochemical identification, the catalase, oxidase, triple sugar iron, and citrate utilisation tests were run. Using the Kirby Bauer Disc diffusion technique, antibiotic resistance was revealed. Pseudomonas aeruginosa was most prevalent in group C males (51-100 years old) and group B females (60.7%), (19-50 ages). The Clinical samples were divided as follows: pus (40.6%), urine (16.2%), sputum (16.2%), sputum (10.5%), wound (4.8%) and blood (3.2%). According to the antimicrobial resistance pattern, from 6 antibiotics of different classes, Ceftazidime (90%) and cefotaxime (86%) showed high resistance. In contrast, Meropenem (12%), Levofloxacin (16%), and Ciprofloxacin (24%) showed sensitivity, and Gentamicin (30%) was intermediate against P. aeruginosa. Our outcome specifies that P. aeruginosa was highly resistant to some commonly prescribed antibiotics. The selection and reasonable application of antimicrobial drugs in hospital settings for first therapy would be beneficial in preventing the further spread of resistance as the incidence of isolates of P. aeruginosa raises over time.

Publisher

MedCrave Group Kft.

Subject

General Materials Science

Reference49 articles.

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