Affiliation:
1. 1 Szent István University Department of Pathology and Forensic Veterinary Medicine István u. 2 H-1078 Budapest Hungary
2. 2 Szent István University Department and Clinic of Internal Medicine, Faculty of Veterinary Science István u. 2 H-1078 Budapest Hungary
Abstract
A heterotopic in situ complex adenocarcinoma developing on the hindlimb is reported for the first time from an Asian Leaf Turtle (Cyclemys dentata). The tumour mechanically hampered the movement of the animal. The turtle refused to eat and consequently developed a poor condition. Histopathology of the tumour revealed all characteristics of a well-differentiated adenocarcinoma originating from apocrine gland-like tissue: the irregular, tubular structures varying in size were generally lined by two to four layers of cuboidal to columnar neoplastic epithelial cells. Claudin-5, pancytokeratin, cytokeratin, vimentin, α-SMA and Ki-67 immunohistochemical antibodies were employed for characterising the tumour. The diagnosis was a complex adenocarcinoma originating from apocrine gland-like tissue in a turtle.
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