Affiliation:
1. 1 National Research Institute of Animal Production Department of Immuno- and Cytogenetics Krakowska 1 32-083 Balice/Kraków Poland
2. 2 Agricultural University of Poznań Department of Genetics and Animal Breeding Poland
3. 3 Vetsuisse Faculty University of Zurich Swiss Federal Institute of Technology Zurich and Department of Animal Science Switzerland
Abstract
An infertile mare with hypoplastic ovaries was subjected to cytogenetic analysis. Fluorescence
in situ
hybridisation (FISH) using the equine X whole chromosome painting probe (WCPP) was carried out on a chromosome preparation obtained from blood lymphocyte culture. The number of analysed spreads was high (235) and in the X chromosome aneuploidy in mosaic form was diagnosed. The karyotype formula was 63,X / 64,XX / 65,XXX. The ratio of the three lines was 15%, 82% and 3%, respectively. The application of the FISH technique with WCPP is discussed.
Reference14 articles.
1. Detection of equine X chromosome abnormalities in equids using a horse X whole chromosome paint probe (WCPP);Breen M.;Vet. J.,1997
2. Expression of genes from the human active and inactive X chromosomes;Brown C. J.;Am. J. Hum. Genet.,1997
3. Nonmosaic X trisomy, detected by chromosome painting, in an infertile mare;Bugno M.;Equine Vet. J.,2003
4. Two cases of subfertile mares with 64,XX/63,X mosaic karyotype;Bugno M.;Ann. Anim. Sci.,2001
5. Chromosome abnormalities as a cause of infertility in mares;Chandley A. C.;J. Reprod. Fertil., Suppl.,1975
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