Secondary tumoural valvulopathy in a dog

Author:

Jakab Csaba1,Szász Attila2,Kulka Janina2,Baska Ferenc1,Rusvai Miklós1,Gálfi Péter3,Németh Tibor4

Affiliation:

1. 1 Szent István University Department of Pathology and Forensic Veterinary Medicine, Faculty of Veterinary Medicine István u. 2 H-1078 Budapest Hungary

2. 2 Semmelweis University 2nd Department of Pathology Budapest Hungary

3. 3 Szent István University Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine István u. 2 H-1078 Budapest Hungary

4. 4 Szent István University Department of Surgery and Ophthalmology, Faculty of Veterinary Medicine István u. 2 H-1078 Budapest Hungary

Abstract

This short report describes a case of tricuspid valvular metastasis of canine disseminated histiocytic sarcoma in a 9-year-old female Rottweiler. Immunohistochemically the malignant neoplastic cells gave a strong reaction for vimentin and lysozyme, and showed negativity for serotonin, CD3, CD79a and cytokeratin. The intratumoural microvessels were detected by immunohistochemistry using CD31 and claudin-5. This appears to be the first report of a valvular metastasis of canine malignant histiocytosis.

Publisher

Akademiai Kiado Zrt.

Subject

General Veterinary

Reference6 articles.

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