Changes in epidemiology, etiology, diagnostics, and therapy of acute appendicitis

Abstract

The frequency of acute appendicitis has fallen in the last three decades in developed industrialized countries. From 1961 to 1991 the number of appendectomies performed annually in Hungary decreased significantly. Since 1991 the numbers are essentially unchanged. Appendix lumen obstruction was formerly believed to be crucial in the etiology of the illness, while today mixed aerobic, anaerobic bacterial infection is considered more important. The inflammation process – according to immunogenetic differences – may lead to recovery or tissue necrosis and perforation. To date, no methods are known that could timely distinguish spontaneously healing or conservatively treatable appendicitis from those resulting in tissue necrosis, although routine usage of abdominal ultrasound technique is added to the clinical picture’s modern diagnostic arsenal. The operation method for removing the appendix also changed. Experiences confirmed that laparoscopic appendectomy is usually more favorable in the treatment of acute appendicitis than traditional surgery.