A simple and sensitive HPLC method for simultaneous quantification of macrocyclic spermidine alkaloids in root, stem and leaf of Tripterygium wilfordii-Reference-Cited by-同舟云学术

A simple and sensitive HPLC method for simultaneous quantification of macrocyclic spermidine alkaloids in root, stem and leaf of Tripterygium wilfordii

Published:2023-04-25 Issue:2 Volume:35 Page:139-143
ISSN:1233-2356
Container-title:Acta Chromatographica
language:
Short-container-title:AChrom

Author:

Zhang Liang¹²,Xu Weiwei¹,Jiang Hongxia¹,Liu Jianqun¹^ORCID

Affiliation:

1. Key Laboratory of Modern Preparation of TCM, Ministry of Education, Jiangxi University of Chinese Medicine, Nanchang, 330004, China

2. College of Animal Pharmaceutical Sciences, Jiangsu Agri-animal Husbandry Vocational College, Taizhou, 225300, China

Abstract

AbstractThere has been a lively interest on macrocyclic polyamine alkaloids due to their remarkable pharmacological activities such as anti-tumor, anti-inflammatory, anti-Alzheimer's disease and anti-parasitic. Tripterygium wilfordii is a widely used traditional Chinese medicine, which is abundant in alkaloids including macrocyclic polyamine alkaloids. However, there are rarely studies on macrocyclic spermidine alkaloids of T. wilfordii so far. In this article, we use three known macrocyclic spermidine alkaloids celafurine, celabenzine and celacinnine, and successfully develop a simple and sensitive HPLC method for simultaneous quantification of macrocyclic spermidine alkaloids in root, stem and leaf of T. wilfordii.

Funder

Project for Academic and Technical Leaders of Major Disciplines in Jiangxi

National Natural Science Foundation of China

Publisher

Akademiai Kiado Zrt.

Subject

General Chemistry

Link

https://akjournals.com/downloadpdf/journals/1326/35/2/article-p139.xml

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