Lymphogranuloma venereum – the first Hungarian cases

Author:

Bánvölgyi András1,Balla Eszter2,Bognár Péter1,Tóth Béla1,Ostorházi Eszter1,Bánhegyi Dénes3,Kárpáti Sarolta1,Marschalkó Márta1

Affiliation:

1. Semmelweis Egyetem, Általános Orvostudományi Kar Bőr-, Nemikórtani és Bőronkológiai Klinika Budapest Mária u. 41. 1085

2. Országos Epidemiológiai Központ II. Bakteriológiai Osztály, STI Laboratórium Budapest

3. Egyesített Szent László és Szent István Kórház V. Infektológiai Osztály Budapest

Abstract

Lymphogranuloma venereum is a sexually transmitted infection caused by the Chlamydia trachomatis serovars L1–3. It has been found to be endemic in tropical countries. In the last decades several cases have been reported in Western Europe, particularly in men who have sex with men population infected with human immunodeficiency virus. The authors present three cases of lymphogranuloma venereum infections, observed at their department in 2013 and 2014. The three human immunodeficiency virus infected patients who belonged to men who have sex with men population had casual sexual contacts in Western Europe. The symptoms included urethral discharge, discomfort and inguinal lymphadenomegaly in two patients, and rectal pain, discharge and perianal ulceration in one patient. The diagnosis was confirmed by nucleic acid amplification test performed in samples obtained from urethral discharge and exudate of perianal ulcer; lymphogranuloma venereum 2b serovars were demonstrated in two patients and serovar 2 in one patient. Doxycyclin (daily dose of two times 100 mg for 21 days) resolved the symptoms in all cases. The authors conclude that lymphogranuloma venereum is a diagnostic challenge in Hungary, too. It is important to be aware of the altered clinical features of this disease to prevent complications and spreading. Orv. Hetil., 2015, 156(1), 36–40.

Publisher

Akademiai Kiado Zrt.

Subject

General Medicine

Reference25 articles.

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3. Durand, M., Nicolas, J., Favre, M., et al.: Lymphogranulomatose inguinale, subaiguë d’origine génitale probable, peut-être vénérienne. Bull. et mém. Soc. Méd. d. hôp. de Par., 1913, 35, 274–288.

4. Melczer, M.: The fourth venereal disease. [A negyedik nemibetegség.] Magyar Orvosi Tankönyvkiadó Társulat, Budapest, 1938. [Hungarian]

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