Deficiency of tPA Exacerbates White Matter Damage, Neuroinflammation, Glymphatic Dysfunction and Cognitive Dysfunction in Aging Mice-Reference-Cited by-同舟云学术

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Deficiency of tPA Exacerbates White Matter Damage, Neuroinflammation, Glymphatic Dysfunction and Cognitive Dysfunction in Aging Mice

Published:2019 Issue:4 Volume:10 Page:770
ISSN:2152-5250
Container-title:Aging and disease
language:en
Short-container-title:Aging and disease

Author:

Yu Peng,Venkat Poornima,Chopp Michael,Zacharek Alex,Shen Yi,Liang Linlin,Landschoot-Ward Julie,Liu Zhongwu,Jiang Rongcai,Chen Jieli

Publisher

Aging and Disease

Subject

Cell Biology,Neurology (clinical),Geriatrics and Gerontology,Pathology and Forensic Medicine

Link

http://www.aginganddisease.org/fileup/2152-5250/PDF/ad-0-0-0-1808221134-1.pdf

Reference63 articles.

1. Cheng JW, Zhang XJ, Cheng LS, Li GY, Zhang LJ, Ji KX, et al. (2018). Low-Dose Tissue Plasminogen Activator in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis. J Stroke Cerebrovasc Dis, 27: 381-390.

2. Bi Oh S, Suh N, Kim I, Lee JY (2015). Impacts of aging and amyloid-beta deposition on plasminogen activators and plasminogen activator inhibitor-1 in the Tg2576 mouse model of Alzheimer's disease. Brain Res, 1597: 159-167.

3. Suzuki Y, Yasui H, Brzoska T, Mogami H, Urano T (2011). Surface-retained tPA is essential for effective fibrinolysis on vascular endothelial cells. Blood, 118: 3182-3185.

4. Chapin JC, Hajjar KA (2015). Fibrinolysis and the control of blood coagulation. Blood Rev, 29: 17-24.

5. Ben Shimon M, Zeimer T, Shavit Stein E, Artan-Furman A, Harnof S, Chapman J, et al. (2017). Recovery from trauma induced amnesia correlates with normalization of thrombin activity in the mouse hippocampus. PLoS One, 12: e0188524.

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