Targeting Sclerostin and Dkk1 at Optimized Proportions of Low-Dose Antibody Achieves Similar Skeletal Benefits to Higher-Dose Sclerostin Targeting in the Mature Adult and Aged Skeleton-Reference-Cited by-同舟云学术

Targeting Sclerostin and Dkk1 at Optimized Proportions of Low-Dose Antibody Achieves Similar Skeletal Benefits to Higher-Dose Sclerostin Targeting in the Mature Adult and Aged Skeleton

Published:2022 Issue:6 Volume:13 Page:1891
ISSN:2152-5250
Container-title:Aging and disease
language:en
Short-container-title:Aging and disease

Author:

Choi Roy B.,Hoggatt April M.,Horan Daniel J.,Rogers Emily Z.,Hong Jung Min,Robling Alexander G.

Publisher

Aging and Disease

Subject

Cell Biology,Neurology (clinical),Geriatrics and Gerontology,Pathology and Forensic Medicine

Link

http://www.aginganddisease.org/fileup/2152-5250/PDF/1655167577302-2105387429.pdf

Reference29 articles.

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3. Li H, Xiao Z, Quarles LD, Li W (2021). Osteoporosis: Mechanism, Molecular Target and Current Status on Drug Development. Curr Med Chem, 28(8):1489-1507.

4. Broadhead ML, Clark JC, Dass CR, Choong PF, Myers DE (2011). Therapeutic targeting of osteoclast function and pathways. Expert Opin Ther Targets, 15(2):169-181.

5. Montagnani A (2014). Bone anabolics in osteoporosis: Actuality and perspectives. World J Orthop, 5(3):247-254.

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