Decreased Naïve T-cell Production Leading to Cytokine Storm as Cause of Increased COVID-19 Severity with Comorbidities
Author:
Publisher
Aging and Disease
Subject
Cell Biology,Clinical Neurology,Geriatrics and Gerontology,Pathology and Forensic Medicine
Link
http://www.aginganddisease.org/fileup/2152-5250/PDF/ad-0-0-0-2006230757-1.pdf
Reference17 articles.
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2. Diao B, Wang C, Tan Y, Chen X, Liu Y, Ning L, et al. (2020). Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19). Front Immunol, 11:827.
3. Montecino-Rodriguez E, Berent-Maoz B, Dorshkind K (2013). Causes, consequences, and reversal of immune system aging. J Clin Invest, 123:958-65.
4. Palmer DB (2013). The effect of age on thymic function. Front Immunol, 4:316.
5. Ringhoffer S, Rojewski M, Döhner H, Bunjes D, Ringhoffer M (2013). T-cell reconstitution after allogeneic stem cell transplantation: assessment by measurement of the sjTREC/βTREC ratio and thymic naive T cells. Haematol Hematol J, 98:1600-8.
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