A Guide to the Perplexed on the Specificity of Antibodies-Reference-Cited by-同舟云学术

A Guide to the Perplexed on the Specificity of Antibodies

Published:2008-09-15 Issue:1 Volume:57 Page:1-5
ISSN:0022-1554
Container-title:Journal of Histochemistry & Cytochemistry
language:en
Short-container-title:J Histochem Cytochem.

Author:

Saper Clifford B.¹

Affiliation:

1. Department of Neurology and Program in Neuroscience, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, Massachusetts

Abstract

Many investigators are unaware of the potential problems with specificity of antibodies and the need to document antibody characterization meticulously for each antibody that is used. In this review, I consider the principles of antibody action and how they define a set of rules for what information should be obtained by the investigator before using an antibody in a serious scientific investigation.

Publisher

SAGE Publications

Subject

Histology,Anatomy

Link

http://journals.sagepub.com/doi/pdf/10.1369/jhc.2008.952770

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