1. Department of Pathology (STsuge,YM,KS,KI,YT), Fujita Health University School of Medicine, Toyoake, Aichi, Japan
2. Department of Oral and Maxillofacial Surgery (STsuge), Fujita Health University School of Medicine, Toyoake, Aichi, Japan
3. Cell-Free Science and Technology Research Center, Ehime University, Matsuyama, Japan (KM,TS,YE)
4. Proteo-Medicine Research Center, Ehime University, Toon, Japan (TS,YE)
5. Department of Pathophysiology–Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan (KN,HM,STakashiba)