VUV-photon Induced Formation of Hydrophilic and Hydrophobic Micro Domains Structure on Intraocular Lens Surface for Blocking after Cataract

Abstract

ABSTRACTA micro domain structure, which hydrophilic and hydrophobic groups were arrayed alternately, was formed on the surface of an intraocular lens [IOL] by using ultra violet rays [VUV]. With this technique, the IOL that is free from fibrin has been developed. In order to substitute the hydrophilic groups in matrix-form on the surface, an ArF laser light was then irradiated on the hydrophobic surface in the presence of water for the −OH groups, through the 50-micrometer dot-patterned reticle. With this selective photochemical surface modification, the hydrophilic and hydrophobic groups were arrayed alternately on the sample surface. The modified IOL was soaked in 0.1-wt % fibrin solutions, and the fibrin-sticking rate was measured by using an infrared spectroscopy [FT-IR]. It results that the absorption coefficient of amide band reached to 0.0006, decreasing to one-six of non-treatment sample's.