Author:
Tong Rong,Christian David A.,Tang Li,Cabral Horacio,Baker James R.,Kataoka Kazunori,Discher Dennis E.,Cheng Jianjun
Abstract
AbstractPolymers have been extensively utilized in the design of nanometer-sized delivery vehicles of chemotherapeutics for clinical cancer therapy. Polymeric nanoparticulate delivery vehicles, with chemotherapeutics being either conjugated or encapsulated, have been developed into a variety of different architectures, including polymer-drug conjugates with linear or branched polymers, micelles, and polymersomes. This review describes the progress that has been made in the field of polymeric nanomedicine that brings the science closer to clinical realization of nanopolymeric therapeutics for its application in cancer treatment.
Publisher
Springer Science and Business Media LLC
Subject
Physical and Theoretical Chemistry,Condensed Matter Physics,General Materials Science
Cited by
52 articles.
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