Kounis Syndrome: Is it a Heralder or Just a Mimicker of Acute Coronary Syndrome?

Abstract

Coronary vasospasm of allergic aetiology is a heavily underdiagnosed condition. Very few instances of this phenomenon are reported. This is a case of a 55-year-old male, with an unusual presentation, where a bee sting triggered an allergic inflammatory reaction, leading to release of inflammatory cytokines resulting in coronary vasospasm. This is evidenced by ST segment elevations at the time of presentation. This ST segment changes resolves on taking antihistaminic and corticosteroid medication. The resolution of symptoms and Electrocardiogram (ECG) findings after treatment with antihistaminic and corticosteroid proved that, the symptoms were primarily caused by an allergic reaction. The present case report explained that, coronary vasospasm can occur due to hypersensitivity reactions and can be treated promptly with antihistaminic and immunosuppressive (hydrocortisone) drugs.