Verrucous Hyperplasia Masquerading as a Verrucous Carcinoma: A Diagnostic Challenge

Abstract

Verrucous Hyperplasia (VH) is a rare exophytic oral mucosal lesion that can progress to Verrucous Carcinoma (VC) and it has increased probability of converting into Squamous Cell Carcinoma (SCC). These lesions present diagnostic difficulties to the clinician. In diagnosing this, histopathology remains the gold standard. In VH cases, these entities can be distinguished by the lack of invasive growth; as a result, when performing a biopsy of the lesion's epithelium, it is critical to include a margin with adequate depth. Therefore, it is pivotal that biopsies of verrucous lesions include a lesional margin with adequate depth. The present case report discusses about the VH, a 53-year-old male patient presented with a complaint of non healing growth in the left lower back tooth region. During clinical examination, well-defined oval soft growth with cauliflower like projections on the surface was present and measured 2×1 cm with well-defined borders. Treatment plan includes surgical excision. The lesion was sent for histopathological examination and the final diagnosis was made. The patient was reviewed for three months, no recurrence of the lesion was observed during the follow-up period.