Co-morbidities of Nocturia among Adults: A Cross-sectional Study in Southern India

Abstract

Introduction: Night urination severely impacts the quality of life among adults. Coexisting factors such as age, obesity, diabetes, hypertension, cardiac diseases, UTI, asthma, anxiety, and depression are significantly related when voiding episodes exceed two per night. However, understanding its associated factors are essential aspects in the management of Nocturia. Aim: The aim of the study was to determine the association of nocturia with selected demographic variables, co-morbidities, and the precipitating factors among adults with voiding episodes two or more times and adults who void only once at night. Materials and Methods: A descriptive cross-sectional design was carried out among 420 adults of age 35-65 years with voiding over two times (Group I) and 206 adults of age 35-65 years who voided only once (Group II) a night. The data was collected from two selected hospitals of Mangalore between January 2018 and June 2019. The written permission was taken from the concerned authority, after obtaining the informed consent from the subjects. The baseline proforma was assessed by the researcher using structured interview schedule and the questionnaire on co-morbidity and precipitating factors such as regular intake of alcoholism, smoking, consumption of coffee, spicy food, anxiety, urinate before bedtime, use of diuretics, day time frequency, underwent surgeries was filled by the subjects. The data was analysed using frequency, percentage, Chi-square test, and logistic regression statistics by Statistical Package for the Social Sciences (SPSS) Version 16. Results: The study observed that the risk of nocturia was significantly higher among Group I subjects with Urinary Tract Infection (UTI), constipation, hypertension, and on medication for various diseases compared with Group II. The precipitating factors of nocturia revealed that Group I subjects who regularly took coffee, spicy food, had anxiety, daytime frequency, and had undergone various surgeries showed significant difference associated with increased risk of nocturia compared with Group II. Conclusion: The study findings demonstrate that nocturia is strongly associated with multiple co-morbidities and precipitating factors. These results therefore provide evidence to establish the primary and secondary preventive strategies among adults with nocturia.