P-Glycoprotein (ABCB1) Inhibits the Influx and Increases the Efflux of 11C-Metoclopramide Across the Blood–Brain Barrier: A PET Study on Nonhuman Primates-Reference-Cited by-同舟云学术

P-Glycoprotein (ABCB1) Inhibits the Influx and Increases the Efflux of 11C-Metoclopramide Across the Blood–Brain Barrier: A PET Study on Nonhuman Primates

Published:2018-05-10 Issue:10 Volume:59 Page:1609-1615
ISSN:0161-5505
Container-title:Journal of Nuclear Medicine
language:en
Short-container-title:J Nucl Med

Author:

Auvity Sylvain,Caillé Fabien,Marie Solène,Wimberley Catriona,Bauer Martin,Langer Oliver,Buvat Irène,Goutal Sébastien,Tournier Nicolas

Publisher

Society of Nuclear Medicine

Subject

Radiology Nuclear Medicine and imaging

Reference34 articles.

1. Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

2. Imaging the Function of P-Glycoprotein With Radiotracers: Pharmacokinetics and In Vivo Applications

3. Structure and function of the blood–brain barrier

4. Membrane transporters in drug development

5. P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

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