Synthesis of the PET Tracer 124I-Trametinib for MAPK/ERK Kinase Distribution and Resistance Monitoring-Reference-Cited by-同舟云学术

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Synthesis of the PET Tracer 124I-Trametinib for MAPK/ERK Kinase Distribution and Resistance Monitoring

Published:2020-05-22 Issue:12 Volume:61 Page:1845-1850
ISSN:0161-5505
Container-title:Journal of Nuclear Medicine
language:en
Short-container-title:J Nucl Med

Author:

Pratt Edwin C.,Isaac Elizabeth,Stater Evan P.,Yang Guangbin,Ouerfelli Ouathek,Pillarsetty Nagavarakishore,Grimm Jan

Publisher

Society of Nuclear Medicine

Subject

Radiology, Nuclear Medicine and imaging

Reference20 articles.

1. Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions

2. Improved Overall Survival in Melanoma with Combined Dabrafenib and Trametinib

3. GSK1120212 (JTP-74057) Is an Inhibitor of MEK Activity and Activation with Favorable Pharmacokinetic Properties for Sustained In Vivo Pathway Inhibition

4. A combinatorial strategy for treating KRAS-mutant lung cancer

5. NK cell–mediated cytotoxicity contributes to tumor control by a cytostatic drug combination

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1. Virtual screening, molecular docking, MD simulation studies, DFT calculations, ADMET, and drug likeness of Diaza-adamantane as potential MAPKERK inhibitors;Frontiers in Pharmacology;2024-07-02

2. Effect of NFX-179 MEK inhibitor on cutaneous neurofibromas in persons with neurofibromatosis type 1;Science Advances;2024-05-03

3. Serine/threonine-protein kinase B-Raf inhibitors;Current Molecular Targets of Heterocyclic Compounds for Cancer Therapy;2024

4. Simultaneous quantitative imaging of two PET radiotracers via the detection of positron–electron annihilation and prompt gamma emissions;Nature Biomedical Engineering;2023-07-03

5. Translating Molecules into Imaging—The Development of New PET Tracers for Patients with Melanoma;Diagnostics;2022-04-29

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