Author:
Pondelis Nicholas J.,Moulton Eric A.
Abstract
Supraspinal mechanisms of pain are increasingly understood to underlie neuropathic ocular conditions previously thought to be exclusively peripheral in nature. Isolating individual causes of centralized chronic conditions and differentiating them is critical to understanding the mechanisms underlying neuropathic eye pain and ultimately its treatment. Though few functional imaging studies have focused on the eye as an end-organ for the transduction of noxious stimuli, the brain networks related to pain processing have been extensively studied with functional neuroimaging over the past 20 years. This article will review the supraspinal mechanisms that underlie pain as they relate to the eye.
Reference278 articles.
1. The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises;Raja;Pain.,2020
2. What is this thing called pain?;Woolf;J Clin Invest.,2010
3. Nociception, pain, negative moods, and behavior selection;Baliki;Neuron.,2015
4. Sensory, motivational, and central control determinants of pain: a new conceptual model;Melzack;The skin senses.,1968
5. Distraction modulates connectivity of the cingulo-frontal cortex and the midbrain during pain–an fMRI analysis;Valet;Pain.,2004
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