Author:
Yue Yongwei,Meng Lijun,Ling Jing,Fan Liyan,Zhang Yanlei,Hu Yixin,Chang Alex H.,Hu Shaoyan
Abstract
NK cells have important functions in resisting cytomegalovirus infection, as they proliferate after viral infection and have certain immunological memory. Here, we report infusion of haploid donor-derived natural killer cells to treat two pediatric patients with Wiskott-Aldrich syndrome (WAS) who were infected with cytomegalovirus after cord blood transplantation (CBT), which successfully cleared the viral infection in both patients.
Funder
National Natural Science Foundation of China
National Key Research and Development Program of China