Neurorepair and Regeneration of the Brain: A Decade of Bioscaffolds and Engineered Microtissue

Abstract

Graphical AbstractBioscaffolds potential applications in tissue engineering. Bioscaffolds can be used to grow stem cells and target their differentiation in vitro(upper, left) or be used as stem cell delivery route in a brain injury (upper, right). Bioscaffolds can also contain si/miRNAs that will modify locally neural cells gene expression (lower, left) or contain exosomes/growth factors for paracrine signaling such as stimulating neurogenesis and increase neural stem migration to injury area (lower, right). This cover has been designed using resources created by Vitaly Gorbachev from Flaticon.com.