Author:
Cao Dehong,Naiyila Xiaokaiti,Li Jinze,Huang Yin,Chen Zeyu,Chen Bo,Li Jin,Guo Jianbing,Dong Qiang,Ai Jianzhong,Yang Lu,Liu Liangren,Wei Qiang
Abstract
A tumor microenvironment (TME) is composed of various cell types and extracellular components. It contains tumor cells and is nourished by a network of blood vessels. The TME not only plays a significant role in the occurrence, development, and metastasis of tumors but also has a far-reaching impact on the effect of therapeutics. Continuous interaction between tumor cells and the environment, which is mediated by their environment, may lead to drug resistance. In this review, we focus on the key cellular components of the TME and the potential strategies to improve the effectiveness of drug therapy by changing their related factors.
Funder
Department of Science and Technology of Sichuan Province
Subject
Cell Biology,Developmental Biology
Cited by
5 articles.
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