Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting-Reference-Cited by-同舟云学术

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Mitochondrial and Redox Modifications in Huntington Disease Induced Pluripotent Stem Cells Rescued by CRISPR/Cas9 CAGs Targeting

Published:2020-09-22 Issue: Volume:8 Page:
ISSN:2296-634X
Container-title:Frontiers in Cell and Developmental Biology
language:
Short-container-title:Front. Cell Dev. Biol.

Author:

Lopes Carla,Tang Yang,Anjo Sandra I.,Manadas Bruno,Onofre Isabel,de Almeida Luís P.,Daley George Q.,Schlaeger Thorsten M.,Rego Ana Cristina Carvalho

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Frontiers Media SA

Subject

Cell Biology,Developmental Biology

Reference63 articles.

1. Polyglutamine disease modeling: epitope based screen for homologous recombination using CRISPR/Cas9 system.;An;PLoS Curr.,2014

2. Genetic correction of Huntington’s disease phenotypes in induced pluripotent stem cells [Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov’t].;An;Cell. Stem Cell,2012

3. A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells.;Birket;J. Cell Sci.,2011

4. Using CRISPR-Cas9 to generate gene-corrected autologous iPSCs for the treatment of inherited retinal degeneration.;Burnight;Mol. Ther.,2017

5. The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington’s disease patients demonstrates mutation related enhanced lysosomal activity [Research Support, Non-U.S. Gov’t].;Camnasio;Neurobiol. Dis.,2012

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