Herpes simplex Virus Pneumonitis in an Acute/Subacute Paracoccidioidomycosis Patient With Malabsorption Syndrome. Case-Report and Literature Review
-
Published:2022-02-10
Issue:
Volume:2
Page:
-
ISSN:2673-6128
-
Container-title:Frontiers in Fungal Biology
-
language:
-
Short-container-title:Front. Fungal Biol.
Author:
Cavalcante Ricardo S.,Souza Bruno S.,Duarte Iverson X.,Moraes Marcelo P. T.,Coelho Kunie I. R.,Griva Beatriz L.,Pereira Beatriz A. S.,Calvi Sueli A.,Betini Marluci,Mendes Rinaldo P.
Abstract
Paracoccidioides sp.—Herpes simplex virus (HSV) co-infection was not reported until now and malabsorption syndrome is a rare complication of the acute/subacute form (AF) of paracoccidioidomycosis (PCM), characterized by life-threatening abnormalities, such as fat and protein loss, lymphopenia, ascites, and intense immunosuppression. A 21-year-old woman presented the PCM AF with intense involvement of the abdominal and intestinal lymphoid organs, which leads to the malabsorption syndrome and severe immunosuppression. This patient developed a fatal-disseminated HSV infection associated with the paracoccidioidal disease. This case demonstrates that, in addition to the antigen-specific immunosuppression, some PCM patients can present a generalized cell-mediated immune depression and endogenous infection of latent microorganisms. On the best of our knowledge, this is the first report of an association between PCM and HSV infection.
Publisher
Frontiers Media SA
Subject
General Earth and Planetary Sciences,General Environmental Science
Reference47 articles.
1. Hipoproteinemia em pacientes com paracoccidioidomicose do tubo digestivo e sistema linfático abdominal: revisão de casos de necropsia e apresentação de um caso com perda protéica digestiva;Andrade;Rev. Hosp. Clín. Fac. Méd. Sau Paulo,1976
2. Immunologically privileged sites;Barker;Adv. Immunol,1977
3. Cryptococcosis as an opportunistic infection in immunodeficiency secondary to paracoccidioidomycosis;Benard;Mycopathologia
4. Antigen-specific immunosuppression in paracoccidioidomycosis;Benard;Am J. Trop. Med. Hyg
5. Síndrome de malabsorção na blastomicose sul americana: relato de um caso;Bettarello;Rev. Hosp. Clín. Fac. Med. Sau Paulo,1972
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献