Toward the Identification of Extra-Oral TAS2R Agonists as Drug Agents for Muscle Relaxation Therapies via Bioinformatics-Aided Screening of Bitter Compounds in Traditional Chinese Medicine-Reference-Cited by-同舟云学术

Toward the Identification of Extra-Oral TAS2R Agonists as Drug Agents for Muscle Relaxation Therapies via Bioinformatics-Aided Screening of Bitter Compounds in Traditional Chinese Medicine

Published:2019-07-16 Issue: Volume:10 Page:
ISSN:1664-042X
Container-title:Frontiers in Physiology
language:
Short-container-title:Front. Physiol.

Author:

Luo Mingzhi,Ni Kai,Jin Yang,Yu Zifan,Deng Linhong

Publisher

Frontiers Media SA

Subject

Physiology (medical),Physiology

Reference123 articles.

1. A novel family of mammalian taste receptors.;Adler;Cell,2000

2. Understanding ligand binding to g-protein coupled receptors using multiscale simulations.;Alfonso-Prieto;Front. Mol. Biosci.,2019

3. Taste and smell GPCRs in the lung: evidence for a previously unrecognized widespread chemosensory system.;An;Cell. Signal.,2018

4. The bitter truth about bitter taste receptors: beyond sensing bitter in the oral cavity.;Avau;Acta Physiologica,2016

5. Targeting extra-oral bitter taste receptors modulates gastrointestinal motility with effects on satiation.;Avau;Sci. Rep.,2015

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