Author:
Iwauchi Kota,Tanaka Hiroki,Okazaki Kosuke,Matsuda Yasuhiro,Uratani Mitsuhiro,Morimoto Tsubasa,Nakamura Satoshi
Abstract
Experienced psychiatrists identify people with autism spectrum disorder (ASD) and schizophrenia (Sz) through interviews based on diagnostic criteria, their responses, and various neuropsychological tests. To improve the clinical diagnosis of neurodevelopmental disorders such as ASD and Sz, the discovery of disorder-specific biomarkers and behavioral indicators with sufficient sensitivity is important. In recent years, studies have been conducted using machine learning to make more accurate predictions. Among various indicators, eye movement, which can be easily obtained, has attracted much attention and various studies have been conducted for ASD and Sz. Eye movement specificity during facial expression recognition has been studied extensively in the past, but modeling taking into account differences in specificity among facial expressions has not been conducted. In this paper, we propose a method to detect ASD or Sz from eye movement during the Facial Emotion Identification Test (FEIT) while considering differences in eye movement due to the facial expressions presented. We also confirm that weighting using the differences improves classification accuracy. Our data set sample consisted of 15 adults with ASD and Sz, 16 controls, and 15 children with ASD and 17 controls. Random forest was used to weight each test and classify the participants as control, ASD, or Sz. The most successful approach used heat maps and convolutional neural networks (CNN) for eye retention. This method classified Sz in adults with 64.5% accuracy, ASD in adults with up to 71.0% accuracy, and ASD in children with 66.7% accuracy. Classifying of ASD result was significantly different (p<.05) by the binomial test with chance rate. The results show a 10% and 16.7% improvement in accuracy, respectively, compared to a model that does not take facial expressions into account. In ASD, this indicates that modeling is effective, which weights the output of each image.
Funder
Core Research for Evolutional Science and Technology
Subject
Health Informatics,Medicine (miscellaneous),Biomedical Engineering,Computer Science Applications
Cited by
5 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献