L-Asparaginase Exerts Neuroprotective Effects in an SH-SY5Y-A53T Model of Parkinson’s Disease by Regulating Glutamine Metabolism

Author:

Zhang Qingxi,Gao Yuyuan,Zhang Jiahui,Li You,Chen Jianing,Huang Rui,Ma Guixian,Wang Limin,Zhang Yuhu,Nie Kun,Wang Lijuan

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Guangdong Province

Publisher

Frontiers Media SA

Subject

Cellular and Molecular Neuroscience,Molecular Biology

Reference39 articles.

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2. Metabolic dysfunction in Parkinson’s disease: bioenergetics, redox homeostasis and central carbon metabolism;Anandhan;Brain Res. Bull.,2017

3. Detection of amino acid deprivation in the central nervous system;Anthony;Curr. Opin. Clin. Nutr. Metab. Care,2013

4. Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia;Avramis;Int. J. Nanomedicine,2006

5. α-synuclein oligomers: a new hope;Bengoa-Vergniory;Acta Neuropathol.,2017

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